Pixar's 'Up' Tops Box Office With $68.2 Million Debut

The animated action comedy "Up" took flight with a $68.2 million opening weekend, maintaining a perfect box-office track record for Pixar Animation, whose 10 films all have been commercial and critical hits.

Octomom, 14 Kids Get Reality TV Show

The Southern California woman who gave birth to the world's longest-surviving set of octuplets has reportedly signed a deal to star in a reality television series.

Suspect in Custody in Shooting of Abortion Doctor at Church

Dr. George Tiller, who remained one of the nation's few providers of late-term abortions despite decades of protests and attacks, was shot and killed Sunday in a church where he was serving as an usher.

Schumer: Sotomayor 'Filibuster-Proof'

Democratic senator praises Supreme Court nominee's record, downplays controversial comments

Next Stop, Bankruptcy

General Motors, once the country's largest employer, is expected to file for Chapter 11 bankruptcy protection before the markets open Monday morning

Colorado School District Mulls Random Drug Tests

A Colorado Springs school district is considering random drug tests of high school students in district extracurricular activities, including sports, clubs and musical groups.

Trial Looms for U.S. Suspect in Alleged Jihad Plot

Armed with a handheld video camera, a Georgia university student drove with a friend in April 2005 to Washington, D.C., and captured scenes of the Capitol, the Pentagon and other locations.